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Single family home for sale at 643 Grand Ave, South San Francisco, CA 94080 | MLS# ML82059314 | Listing updated on 2026-09-16
Photo 1 of Single family home for sale at 643 Grand Ave, South San Francisco, CA 94080 | MLS# ML82059314 | Listing updated on 2026-09-16
Photo 2 of Single family home for sale at 643 Grand Ave, South San Francisco, CA 94080 | MLS# ML82059314 | Listing updated on 2026-09-16
Photo 3 of Single family home for sale at 643 Grand Ave, South San Francisco, CA 94080 | MLS# ML82059314 | Listing updated on 2026-09-16
Photo 4 of Single family home for sale at 643 Grand Ave, South San Francisco, CA 94080 | MLS# ML82059314 | Listing updated on 2026-09-16
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Listed by: Jill Penna (415) 244-8630 DRE #01895080 | Christie's International Real Estate Sereno (650) 844-7373

$1,248,000

Monthly Est:$6,212

  • Beds Icon3 Beds
  • Beds Icon
    4 Baths
  • Beds Icon1,630sqft

643 Grand Ave, South San Francisco, CA 94080

$6,212/moEst:

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  • Single Family Residence

  • Built in 1895

  • $-- HOA

  • 3,500 sqft lot

  • $766/sq.ft

Description

Ideally located near Downtown South San Francisco and the cities thriving biotech and life-sciences corridor, 643 Grand Avenue where space, comfort, and a remarkable garden setting come together in the heart of South San Francisco. 643 Grand Avenue offers a spacious and versatile layout with excellent access to major transportation and employment centers. The home features 3 bedrooms and 4 bathrooms, with a private full bathroom for each bedroom. Additional highlights include high ceilings, abundant natural light, hardwood floors, a full basement with ample storage, and a detached 2-car garage equipped with a 220-volt outlet for EV charging. The home also features a wate...

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  • Houzeo last checked: 10 minutes ago
  • Listing updated: September 16, 2026 at 4:21 pm
  • Source: California Regional MLS-CA | MLS#: ML82059314 California Regional MLS-CA

Property Details

  • Status

    Active

  • Type

    Single Family Residence

  • No. of Stories

    2

  • County

    San Mateo County

  • City

    South San Francisco

  • Neighborhood

    --

  • Year Built

    1895

  • HOA Fees

    -

  • Finished Area

    1,630 sqft

  • Lot Size

    3,500 sqft lot

  • Basement Area

    - sqft

  • MLS Name

    California Regional MLS

  • MLS Number

    ML82059314

  • MLS Status

    Active

  • Days on Market

    22

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Facts & Features

Rooms

  • Bedrooms & bathrooms

    Bedrooms: 3

    Bathrooms: 4

Interior

  • Window Features

    Skylights

  • Heating

    Central

  • Sewer

    Public Sewer

  • Cooling

    None

Construction

  • Year Built

    Year Built: 1895

  • Home type

    Single Family Residence

  • Foundation Details

    Slab

  • Roof

    Shingle

Utilities & Energy

  • Water Source

    Public

Price History

DateEventPrice

08/27/2026

Source: mls_logoCalifornia Regional MLS-CA #ML82059314

Listed for Sale

$1,248,000 +122.86%

$766/sqft

09/04/2014

Source: mls_logoCalifornia Regional MLS-CA #ML81415816

Price Increased

$560,000 +1.84%

$344/sqft

09/04/2014

Source: mls_logoCalifornia Regional MLS-CA #ML81415816

Sold

$549,900

$337/sqft

Based on information from California Regional Multiple Listing Service, Inc. as of Sep 20, 2026, 04:45AM and /or other sources. All data, including all measurements and calculations of area, is obtained from various sources and has not been, and will not be, verified by broker or MLS. All information should be independently reviewed and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information. Information being provided is for consumers’ personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. This website may not include listings or property addresses of sellers who have directed their listing brokers to withhold their listing or their property address from display on the Internet. © 2026 California Regional Multiple Listing Service. All Rights Reserved.

Advertising Broker: William Johnson DRE #01463271 | William Johnson Brokerage

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